2010 Lexus GS 450h

The GS packs a lot of amenities into a very reliable 4-door sedan starting with a powerful engine. No GS has an output under 300 hp, which adds a strong performance punch to the sedan. Safety tech includes Lexus's Vehicle Dynamics Integrated Management system, which coordinates a slew of sensors to keep the car headed where the driver intends it to go. For fuel misers, the full-hybrid 450h gets 22 mpg in the city and 25 mpg on the highway, a better than 10% improvement over its gasoline-only siblings.